WHO recommends composition of influenza vaccines for southern hemisphere

influenza vaccines

By Kennedy Nnamani

THE World Health Organization, WHO, has announced the recommended viral composition of influenza vaccines for the 2023 southern hemisphere influenza season. 

The recommendations were made today in a statement issued by the organization, noting that it will be used by national vaccine regulatory agencies and pharmaceutical companies to develop, produce, and license influenza vaccines for the following influenza season.

The organization said that the periodic update of viruses contained in influenza vaccines is necessary for the vaccines to be effective due to the constantly evolving nature of influenza viruses.

The recommendation is based on the advice of a group of experts from WHO Collaborating Centres and WHO Essential Regulatory Laboratories that analyze virus surveillance data generated by the WHO Global Influenza Surveillance and Response System or GISRS.

According to WHO, around a billion people get seasonal influenza every year and the threat of an influenza pandemic is ever-present.

“For this reason, the need to monitor circulating respiratory viruses, including influenza, continues to be critical,” it said.

The year-round surveillance is conducted by GISRS, a global network of over 150 laboratories in 127 countries, areas or territories set up in 1952.  This year, we celebrate its 70th anniversary.

WHO further noted that going forward; GISRS will continue to use its unique position as a global respiratory surveillance network to add value to other respiratory virus threats, including COVID-19, where it has already played a significant role. It will also make use of emerging technologies, for example by expanding genomic surveillance to continue to protect people from the threat of influenza.


WHO recommends that quadrivalent vaccines for use in the 2023 southern hemisphere influenza season contain the following:

Egg-based vaccines

•         an A/Sydney/5/2021 (H1N1) pdm09-like virus;